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Gemcitabine (Gem) is currently the first-line chemotherapeutic drug in management of pancreatic cancer, however the therapeutic efficacy of Gem is limited due to its short half-life and poor cell membrane permeability. Here we designed mesoporous silica vesicles (MSVs) with large pore sizes as a novel drug delivery system. The MSVs were synthesized using cetyltrimethyl ammonium bromide (CTAB) as a...
A highly sensitive sensor for determination of carbamate pesticides based rhodamine B (RB) modified silver nanoparticle (RB-AgNPs) was developed. Compared with the classical method, it combined colorimetric with fluorescence for detecting carbamate pesticides in complex solutions. Carbamate pesticides can inhibit the activity of acetylcholinesterase (AChE), thus preventing the generation of thiocholine...
A systematic investigation of the formation of silica-coated magnetite particles via sol–gel approach was conducted using transmission electron microscope (TEM), X-ray diffraction (XRD) and vibrating sample magnetometer (VSM). The results show that reaction parameters including the type of alcohol, the volume ratio of alcohol to water, the amount of catalyst and the amount of precursor play important...
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