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Purpose of Review There is compelling evidence in the clinical population that long-term weight loss secondary to bariatric surgery is mitigated by the reemergence of maladaptive feeding behaviors and in some cases new onset substance abuse. Recent Findings A review of the current literature suggests that physical restructuring of the GI tract during WLS alters secretion of feeding peptides and...
Objective
Binge‐eating disorder is associated with diminished self‐control, emotional distress, and obesity. In this context, women are nearly twice as likely to develop binge‐eating disorder and depression relative to men. Here, the physiological, psychological, and endocrine parameters were characterized in female rats subjected to a binge‐eating protocol.
Methods
Nonrestricted female Long Evans...
RNA biogenesis has emerged as a powerful biological event that regulates energy homeostasis. In this context insertion of alternative polyadenylation sites (APSs) dictate the fate of newly synthesized RNA molecules and direct alternative splicing of nascent transcripts. Thus APSs serve a mechanistic function by regulating transcriptome expression and function. In this study we employed a novel RNA-Seq...
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