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Glomus tumors are neoplasms that occur only rarely in the head and neck. These tumors are usually distinguished by benign growth characteristics. We present a case of a large intranasal glomus tumor which, at presentation, had eroded through the ethmoid roof to involve the floor of the anterior cranial fossa. The patient was treated with primary external-beam radiotherapy. To our knowledge, this is...
Problem: Given its relative anatomic accessibility, significant interest exists in gene therapy strategies for treating head and neck squamous cell carcinoma (HNSCC). However, extremely inefficient gene transfer limits traditional gene therapy strategies. We propose a novel form of gene therapy, using intratumoral transfer of the human sodium iodide symporter (hNIS) gene coupled with systemic delivery...
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