Search results for: Bo Pang

Items from 1 to 20 out of 247 results

article

Low‐intensity noise exposure takes an essential part in the mechanism of late‐onset hereditary hearing loss caused by Abcc1 mutation

Mengzhu Jiang, Shuai Zhang, Jing Liu, Bo Pang, more

With the development of the social economy, we are exposed to increasing noise in our daily lives. Our previous work found an ABCC1(NM_004996.3:c.A1769G, NP_004987.2:p.N590S) variant which cosegregated with the patients in an autosomal dominant non‐syndromic hearing loss family. At present, the specific mechanism of deafness caused by ABCC1 mutation is still not clear. Using the knock‐in mouse model...

article

Fecal microbiota transplantation alleviates mild‐moderate COVID‐19 associated diarrhoea and depression symptoms: A prospective study of a randomized, double‐blind clinical trial

Xia Jiang, Xian Gao, Jiaqi Ding, Bo Pang, more

Journal of Medical Virology > 96 > 8 > n/a - n/a

Currently, the emergence of the endemic Coronavirus disease (COVID‐19) situation still poses a serious threat to public health. However, it remains elusive about the role of fecal microbiota transplantation in treating COVID‐19. We performed a randomized, double‐blind, placebo‐controlled clinical trial enrolling a cohort of 40 COVID‐19 patients with mild‐moderate symptoms. Our results showed that...

article

Hydrocarbon expulsion mechanism of Lower Cambrian argillaceous source rocks in the Tarim Basin, China

Junqing Chen, Xiaobin Yang, Xingang Zhang, Xiongqi Pang, more

Geological Journal > 59 > 7 > 1998 - 2021

The source of oil and gas in the Tarim Basin's platform has always been controversial. The Lower Cambrian Yurtusi Formation and the Xidashan Formation–Xishanbulak Formation argillaceous source rocks are an important set of oil source series in the basin. Based on the principle of conservation of matter, this paper calculates the hydrocarbon expulsion amount of the source rock. Using a phase state...

article

Dynamic changes of net anthropogenic nitrogen/phosphorus input and its riverine export in the Beijing's subcenter

Xiaoyu Luo, Dingzhi Peng, Wenjian Shang, Yu Gu, more

CLEAN – Soil, Air, Water > 52 > 3 > n/a - n/a

Due to human activities, the overabundance of regional nitrogen/phosphorus (N/P) has a huge impact on ecological environment worldwide. It is necessary to comprehensively understand the human‐induced N/P input and spatiotemporal variations of nutrients in a river. As the adjustment to the spatial structure of Beijing, the Beijing's subcenter is an important strategic position in promoting the coordinated...

article

Molecules in the hippo pathway that regulate Th17 differentiation reveal the severity of ankylosing spondylitis

Xiaohan Xu, Wanlin Liu, Yue Liu, Dongmei Wu, more

International Journal of Rheumatic Diseases > 27 > 1 > n/a - n/a

Aim Ankylosing spondylitis (AS) is a chronic, progressive, and inflammatory autoimmune disease of unknown origin that affects the axial skeleton and sacroiliac joints, resulting in pain and loss of function. AS is characterized by the overdifferentiation of T helper 17 (Th17) cells, which contribute to the development of the disease. The Hippo signaling pathway is an important regulator of Th17 differentiation,...

article

Downscaling wind speed based on coupled environmental factors and machine learning

Yuming Lu, Bingfang Wu, Abdelrazek Elnashar, Nana Yan, more

International Journal of Climatology > 43 > 10 > 4733 - 4755

Wind speed changes impact society and have important implications for climate change studies. Thus, high‐resolution and high‐quality wind speed datasets are necessary for environmental monitoring and ecosystem research. However, there is no complete set of high spatial and temporal resolution wind speed datasets for China. Additionally, it is extremely challenging to produce wind speed data at high...

article

Dipicolinic acid enhances kiwifruit resistance to Botrytis cinerea by promoting phenolics accumulation

Su‐Yan Wang, Yi‐Bo Pang, Yuan Tao, Xin‐Chi Shi, more

Pest Management Science > 79 > 9 > 3177 - 3189

BACKGROUND Kiwifruit is highly susceptible to fungal pathogens, such as Botrytis cinerea, which reduce crop production and quality. In this study, dipicolinic acid (DPA), which is one of the main components of Bacillus spores, was evaluated as a new elicitor to enhance kiwifruit resistance to B. cinerea. RESULTS DPA enhances antioxidant capacity and induces the accumulation of phenolics in B. cinerea...

article

Benzo[d]thiazole Based Wide Bandgap Donor Polymers Enable 19.54% Efficiency Organic Solar Cells Along with Desirable Batch‐to‐Batch Reproducibility and General Applicability

Bo Pang, Chentong Liao, Xiaopeng Xu, Liyang Yu, more

Advanced Materials > 35 > 21 > n/a - n/a

The limited selection pool of high‐performance wide bandgap (WBG) polymer donors is a bottleneck problem of the nonfullerene acceptor (NFA) based organic solar cells (OSCs) that impedes the further improvement of their photovoltaic performances. Herein, a series of new WBG polymers, namely PH‐BTz, PS‐BTz, PF‐BTz, and PCl‐BTz, are developed by using the bicyclic difluoro‐benzo[d]thiazole (BTz) as the...

article

Formation and Loading of a (2S)‐2‐Ethylmalonamyl Starter Unit in the Assembly Line of Polyketide‐Nonribosomal Peptide Hybrid Sanglifehrin A

Zhijun Tang, Bo Pang, Chang Liu, Shengjie Guo, more

Angewandte Chemie International Edition > 62 > 23 > n/a - n/a

Sanglifehrin A (SFA) is a spirolactam‐conjugated, 22‐membered macrolide with remarkable immunosuppressive and antiviral activities. This macrolide is a result of a hybrid polyketide synthase (PKS)‐nonribosomal peptide synthetase (NRPS) assembly line that utilizes (2S)‐2‐ethylmalonamyl as a starter unit. Here, we report that the formation and loading of this starter unit in the SFA assembly line involve...

article

Formation and Loading of a (2S)‐2‐Ethylmalonamyl Starter Unit in the Assembly Line of Polyketide‐Nonribosomal Peptide Hybrid Sanglifehrin A

Zhijun Tang, Bo Pang, Chang Liu, Shengjie Guo, more

Angewandte Chemie > 135 > 23 > n/a - n/a

article

Proteomic and metabolomic approaches elucidate the molecular mechanism of emodin against neuropathic pain through modulating the gamma‐aminobutyric acid (GABA)‐ergic pathway and PI3K/AKT/NF‐κB pathway

Peng Chen, Ning‐yu Huang, Bo Pang, Zeng‐jie Ye, more

Phytotherapy Research > 37 > 5 > 1883 - 1899

Neuropathic pain (NeP) is a major health concern. Due to the complex pathological mechanisms, management of NeP is challenging. Emodin, a natural anthraquinone derivative, exerts excellent analgesic effects. However, its mechanisms of action are still poorly understood. In this study, we investigated the mechanisms underlying pain‐relief effects of emodin in the cerebral cortex using proteomic and...

article

Sieving and hydrothermal pre‐treatments for preparing ultra‐high mechanical strength particleboard

Tong Zhou, Bo Pang, Xue‐Fei Cao, Ningzhong Bao, more

Journal of Applied Polymer Science > 140 > 22 > n/a - n/a

The application of non woody biomass materials in the manufacture of wood‐based panels has been confirmed as an efficient carbon sequestration approach. In this study, reed straw was recommended to produce reed‐based particleboards (RPs). Sieving and hydrothermal pre‐treatments were conducted on the inner layer reed particles to reduce the adverse influence of the waxy layer on the mechanical strength...

article

BN‐Bond‐Embedded Triplet Terpolymers with Small Singlet–Triplet Energy Gaps for Suppressing Non‐Radiative Recombination and Improving Blend Morphology in Organic Solar Cells

Bo Pang, Chentong Liao, Xiaopeng Xu, Shaoqian Peng, more

Advanced Materials > 35 > 17 > n/a - n/a

Suppressing the photon energy loss (E_loss), especially the non‐radiative loss, is of importance to further improve the device performance of organic solar cells (OSCs). However, typical π‐conjugated semiconductors possess a large singlet–triplet energy gap (ΔE_ST), leading to a lower triplet state than charge transfer state and contributing to a non‐radiative loss channel of the photocurrent by the...

article

Poly(lactic acid) based Pearl Layer Moistureproof Membrane for Flexible Laminated Packaging

Ying Ma, Jingming Zhao, Yanqing Wang, Bo Pang, more

Macromolecular Rapid Communications > 44 > 7 > n/a - n/a

The development of bio‐based polymer materials, such as polylactic acid (PLA) ‐based polymers, is an effective strategy to reduce dependence on petrochemical‐based polymers. However, the preparation of bio‐based polymers with high barrier properties is a major challenge. To overcome this challenge, a nacreous layer structure with a ‘ brick and mud ’ pattern is mimicked to improve the overall performance...

article

Analysis of the spatial‐temporal components driving transmission of the severe fever with thrombocytopenia syndrome in Shandong Province, China, 2016–2018

Yao Wang, Bo Pang, Wei Ma, Zengqiang Kou, more

Transboundary and Emerging Diseases > 69 > 6 > 3761 - 3770

Existing models about the spatial‐temporal distribution of the severe fever with thrombocytopenia syndrome (SFTS) entirely concentrate on aggregation, which provides limited knowledge to develop effective measures to control the epidemic of SFTS. This study aimed to identify the main spatial‐temporal components and heterogeneity in different regions in Shandong Province, China. We applied the spatial‐temporal...

article

Ultraductile Cementitious Structural Health Monitoring Coating: Waterborne Polymer Biomimetic Muscle and Polyhedral Oligomeric Silsesquioxane‐Assisted C‐S‐H Dispersion

Bo Pang, Zuquan Jin, Yunsheng Zhang, Zhiyong Liu, more

Advanced Functional Materials > 32 > 51 > n/a - n/a

Cement‐based sensors (CBSs) have demonstrated potential in structural health monitoring (SHM) despite rare applications due to their poor flexibility and sensing accuracy/protection with robustness. Herein, a promising strategy is reported to design a waterborne epoxy resin (WEP)‐modified cement‐based composite coating sensorcapable of simultaneous stable SHM and durable protection. The interpenetrating...

article

Circ‐CBFB exacerbates hypoxia/reoxygenation‐triggered cardiomyocyte injury via regulating miR‐495‐3p in a VDAC1‐dependent manner

Yue‐e Chen, Han Yang, Hu‐bo Pang, Fen‐qing Shang

Journal of Biochemical and Molecular Toxicology > 36 > 11 > n/a - n/a

A large body of literature has identified that circular RNAs play critical roles in regulating the occurrence and development of cardiovascular disease. In the present study, we intended to provide new ideas and perspectives on the functional role of circ‐CBFB in hypoxia/reoxygenation (H/R)‐injured cardiomyocytes. We observed that circ‐CBFB expression was enhanced which was accompanied by a miR‐495‐3p...

article

Closely arranged self‐decoupled MIMO antenna group using orthogonal mode and pattern diversity for 5G mobile terminals

Bo Pang, Xia Ai, Wei Hu, Wen Jiang, more

International Journal of RF and Microwave Computer‐Aided Engineering > 32 > 11 > n/a - n/a

In this article, a novel self‐decoupling method for closely arranged multi‐unit antenna array design is proposed. The orthogonal mode and the pattern diversity are adopted to weaken the electromagnetic coupling between the multi‐antenna elements. To verify the proposed self‐decoupling concept, a closely arranged 4‐port antenna group consisting of dual antenna pairs is designed. One of the antenna...

article

Tribological Behavior of Electrical Connector Sn/Ni/Cu Coating with Intermetallic Compound Layers Under Reciprocating Motion

Na Tyrer, Gary C. Barber, Fan Yang, Bo Pang, more

Advanced Engineering Materials > 24 > 9 > n/a - n/a

Electroplating is one of the most common methods for applying electronic connector coatings. This research investigated the tribological behavior of electroplated multilayer coatings of Sn, Ni, and Cu with and without intermetallic compound layers (IMC), which are intermediate compounds formed between two metals under reciprocating sliding. It is found that heat treatment promotes both Sn/Ni IMC...

article

Comparative pharmacokinetic study of bicalutamide administration alone and in combination with vitamin D in rats

Wenjing Shi, Haixiao Di, Bo Pang, Huixin Jin, more

Acta Chromatographica > 2022 > Vol. 34, no. 4 > 453--460

Bicalutamide (BCL) has been approved for treatment of advanced prostate cancer (Pca), and vitamin D is inevitably used in combination with BCL in Pca patients for skeletal or anti-tumor strategies. Therefore, it is necessary to study the effect of vitamin D application on the pharmacokinetics of BCL. We developed and validated a specific, sensitive and rapid UHPLC–MS/MS method to investigate the pharmacokinetic...

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INFONA - science communication portal

Search results for: Bo Pang

Low‐intensity noise exposure takes an essential part in the mechanism of late‐onset hereditary hearing loss caused by Abcc1 mutation

Fecal microbiota transplantation alleviates mild‐moderate COVID‐19 associated diarrhoea and depression symptoms: A prospective study of a randomized, double‐blind clinical trial

Hydrocarbon expulsion mechanism of Lower Cambrian argillaceous source rocks in the Tarim Basin, China

Dynamic changes of net anthropogenic nitrogen/phosphorus input and its riverine export in the Beijing's subcenter

Molecules in the hippo pathway that regulate Th17 differentiation reveal the severity of ankylosing spondylitis

Downscaling wind speed based on coupled environmental factors and machine learning

Dipicolinic acid enhances kiwifruit resistance to Botrytis cinerea by promoting phenolics accumulation

Benzo[d]thiazole Based Wide Bandgap Donor Polymers Enable 19.54% Efficiency Organic Solar Cells Along with Desirable Batch‐to‐Batch Reproducibility and General Applicability

Formation and Loading of a (2S)‐2‐Ethylmalonamyl Starter Unit in the Assembly Line of Polyketide‐Nonribosomal Peptide Hybrid Sanglifehrin A

Formation and Loading of a (2S)‐2‐Ethylmalonamyl Starter Unit in the Assembly Line of Polyketide‐Nonribosomal Peptide Hybrid Sanglifehrin A

Proteomic and metabolomic approaches elucidate the molecular mechanism of emodin against neuropathic pain through modulating the gamma‐aminobutyric acid (GABA)‐ergic pathway and PI3K/AKT/NF‐κB pathway

Sieving and hydrothermal pre‐treatments for preparing ultra‐high mechanical strength particleboard

BN‐Bond‐Embedded Triplet Terpolymers with Small Singlet–Triplet Energy Gaps for Suppressing Non‐Radiative Recombination and Improving Blend Morphology in Organic Solar Cells

Poly(lactic acid) based Pearl Layer Moistureproof Membrane for Flexible Laminated Packaging

Analysis of the spatial‐temporal components driving transmission of the severe fever with thrombocytopenia syndrome in Shandong Province, China, 2016–2018

Ultraductile Cementitious Structural Health Monitoring Coating: Waterborne Polymer Biomimetic Muscle and Polyhedral Oligomeric Silsesquioxane‐Assisted C‐S‐H Dispersion

Circ‐CBFB exacerbates hypoxia/reoxygenation‐triggered cardiomyocyte injury via regulating miR‐495‐3p in a VDAC1‐dependent manner

Closely arranged self‐decoupled MIMO antenna group using orthogonal mode and pattern diversity for 5G mobile terminals

Tribological Behavior of Electrical Connector Sn/Ni/Cu Coating with Intermetallic Compound Layers Under Reciprocating Motion

Comparative pharmacokinetic study of bicalutamide administration alone and in combination with vitamin D in rats

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