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ObjectivesTreatment simplification involving induction with a ritonavir (RTV)‐boosted protease inhibitor (PI) replaced by a nonboosted PI (i.e. atazanavir) has been shown to be a viable option for long‐term antiretroviral therapy. To evaluate the clinical evidence for this approach, we conducted a systematic review and meta‐analysis of randomized controlled trials (RCTs) evaluating efficacy and safety...
ObjectivesHepatitis C virus (HCV) has emerged as an important health problem in the era of effective HIV treatment. However, very few data exist on the health status and disease burden of HIV/HCV‐coinfected Canadians.
MethodsHIV/HCV‐coinfected patients were enrolled prospectively in a multicentre cohort from 16 centres across Canada between 2003 and 2010 and followed every 6 months. We determined...
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