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Ulcerative colitis is a chronic recurrent disease characterized by acute inflammation of the colonic mucosa. In Japan, a dietary supplementation product enriched with glutamine, dietary fiber, and oligosaccharide (GFO) is widely applied for enteral nutrition support. These three components have been suggested to improve intestinal health. In this study, we investigated whether GFO has suppressive...
The structure of monochorionic twin placentae with and without twin-twin transfusion syndrome (TTTS) was studied in mice at 17 days gestation. The TTTS donor showed anemia and growth retardation, while the TTTS recipient evidenced polycythemia and active secretion of amniotic fluid. The histological architecture of the donor placental labyrinth in TTTS showed a failure of the labyrinth to develop...
The mouse placenta consists of fetal blood vessels, interpolating trophoblast cells and maternal blood spaces forming a labyrinth. It was observed that in contrast to the rapid growth of fetuses, the placentae maintained a constant size through pregnancy. The weight ratio of fetus/placenta was 30:1 at birth about 5 times that in humans. To investigate the efficiency of the labyrinth in materno-fetal...
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