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The authors prepared 7.5% and 12.5% collagen gel, and supplemented it with the tripeptide Gly-His-Lys (GHK), perfloxacine and hypersulphated glycosaminoglycan (HSGAG). By means of 125 I marking, its absorption was followed from small polyurethane sponges placed under the skin of rats. The absorption of gel without HSGAG was found to be faster. Antibodies against collagen (type...
Three composite materials based on collagen gel prepared with ISC 40 and supplemented with the tripeptide glycine-histidine-lysine (GHK) mixed with bioglass (BAS O), pure hydroxyapatite (grain: 0.5-1.0 μm and 13-23 μm) and shredded beef bone were tested in the laboratory rat and guinea-pig. In the course of 49 d, no signs of infectious inflammation or incompatibility were observed around...
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