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DBS of the STN improves quality of life (QoL) and motor function not only in advanced Parkinson's disease (PD), but also in PD with early motor complications, as shown in the recent EARLYSTIM study. In spite of the evidence in favor of STN‐DBS, the findings of the EARLYSTIM study have recently been controversially debated. Here, we argue that a placebo or lessebo effect is unlikely to have relevantly...
Subthalamic nucleus (STN) stimulation in advanced Parkinson’s disease is a very powerful treatment for a highly selected group of patients. However, behavioral problems after neurosurgery have frequently been reported and may hamper the therapeutic success. In particular, impulsivity and impulse control disorders are often discussed as adverse effects of STN stimulation, and there is an ongoing debate...
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