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Essential hypertension is considered to be a multifactorial trait resulting from the combined influence of environmental and genetic determinants. The aim of the study is to assess the association between the human AGTR1 gene and essential hypertension (EH) using a haplotype-based case-control study in Han Chinese subjects.Seven tag SNPs and the A1166C polymorphism of the AGTR1 gene were genotyped...
Mammalian heart has been reported to express AC isozymes (types V and VI) that are inhibited by < μM [Ca 2+ ]; avian heart has been reported to express adenylyl cyclase activity that is inhibited by < μM [Ca 2+ ]. We have used reverse transcription polymerase chain reaction (RT-PCR) to determine that type V and VI AC mRNAs are present in freshly isolated ventricular...
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