Search results for: Zaid Hamdoon

Items from 1 to 20 out of 29 results

article

The consequences and outcomes associated with dental implants encroaching on adjacent teeth

Zaid Hamdoon, Wael Talaat, Ahmed Aziz, Abier Abdul Sattar, more

Clinical Implant Dentistry and Related Research > 23 > 6 > 851 - 856

Background Dental implant placement carries a risk of iatrogenic damage to adjacent root surfaces. Purpose To classify and understand different types of trauma to the tooth root body by dental implants. Materials and Methods This prospective case series included 43 implants placed between February 2017 and June 2020 that had primary stability and were in a position that accidentally invaded the...

article

Apparent Complete Response of a Treatment Refractory and Recurrent Squamous Cell Carcinoma Lesion to Photochemical Internalization: A Clinical Case Study

Waseem Jerjes, Zaid Hamdoon, Kristian Berg, Anders Høgset, more

Photochemistry and Photobiology > 96 > 3 > 680 - 683

Photochemical internalization (PCI) depends on the delivery of sublethal photodynamic reaction to facilitate the work of a chemotherapeutic agent. We discuss our experience in managing a patient with extensive squamous cell carcinoma of the right face and scalp under the TPCS_2a‐based bleomycin PCI treatment protocol. In this case, an 84‐year‐old Caucasian received 0.25 mg kg⁻¹ of TPCS_2a (Amphinex^®...

article

Periorbital skin cancers subjected to mTHPC‐photodynamic therapy: A prospective study

Zaid Hamdoon, Waseem Jerjes, Colin Hopper

Skin Research and Technology > 26 > 3 > 338 - 342

Introduction Photodynamic therapy (PDT) is a relatively new method of treating skin cancers. This prospective study highlights the use of PDT in the management of basal cell carcinomas (BCCs) and T1N0 cutaneous squamous cell carcinomas (SCCs) involving the periorbital area. Materials and methods Surface illumination PDT was offered under local anaesthesia. mTHPC was administered intravenously....

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Structural validation of facial skin using optical coherence tomography: A descriptive study

Waseem Jerjes, Zaid Hamdoon, Colin Hopper

Skin Research and Technology > 26 > 2 > 153 - 162

Background In this immediate ex vivo study, we aimed to identify the structures of normal and pathological facial skin using optical coherence tomography (OCT) and compared them to the gold standard histopathology. Material and Methods A total of 53 patients, with 57 suspicious facial lesions, participated in this study. A set of variables have been highlighted by the pathologist to represent the...

article

Photodynamic therapy in the management of basal cell carcinoma: Retrospective evaluation of outcome

Waseem Jerjes, Zaid Hamdoon, Colin Hopper

Photodiagnosis and Photodynamic Therapy > 2017 > 19 > C > 22-27

Photodynamic therapy (PDT) is a relatively new method of treating various kinds of pathologies. In this retrospective study, a total of 148 patients with basal cell carcinoma (BCC) were treated with surface illumination methyl aminolevulinate – photodynamic therapy (MAL-PDT) or meta-tetrahydroxyphenylchlorin (mTHPC-PDT). Comparisons with the clinical features, rate of recurrence and overall outcome...

article

Photodynamic therapy in the management of actinic keratosis: Retrospective evaluation of outcome

Waseem Jerjes, Zaid Hamdoon, Ali A. Abdulkareem, Colin Hopper

Photodiagnosis and Photodynamic Therapy > 2017 > 17 > C > 200-204

Photodynamic therapy (PDT) is a minimally invasive intervention used in the management of tissue disorders. In this retrospective study, a total of 62 patients with actinic keratosis (AKs) were treated with surface illumination PDT. Comparisons with the clinical features, rate of recurrence as well as malignant transformation and overall outcome were made.The medical records of 62 consecutive patients...

article

Disulfonated tetraphenyl chlorin (TPCS2a)-induced photochemical internalisation of bleomycin in patients with solid malignancies: a phase 1, dose-escalation, first-in-man trial

Ahmed A Sultan, Waseem Jerjes, Kristian Berg, Anders Høgset, more

The Lancet Oncology > 2016 > 17 > 9 > 1217-1229

Photochemical internalisation, a novel minimally invasive treatment, has shown promising preclinical results in enhancing and site-directing the effect of anticancer drugs by illumination, which initiates localised chemotherapy release. We assessed the safety and tolerability of a newly developed photosensitiser, disulfonated tetraphenyl chlorin (TPCS_2a), in mediating photochemical internalisation...

article

Optical coherence tomography in the assessment of oral squamous cell carcinoma resection margins

Zaid Hamdoon, Waseem Jerjes, Gordon McKenzie, Amrita Jay, more

Photodiagnosis and Photodynamic Therapy > 2016 > 13 > C > 211-217

Incomplete surgical removal of cancer is believed to be the main cause of local recurrence and high mortality. This study assessed the use of optical technology (namely optical coherence tomography [OCT]) in examining oral squamous cell carcinoma (OSCC) resection margins to assess if this modality could guide the surgeon during surgical resections.Twenty-eight T₁–T₂ N0M0 oral squamous cell carcinoma...

article

Skeletal and dental relapses after skeletal class III deformity correction surgery: single-jaw versus double-jaw procedures

Raed Al-Delayme, Moutaz Al-Khen, Zaid Hamdoon, Waseem Jerjes

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology > 2013 > 115 > 4 > 466-472

In this prospective comparative study, we looked at the postoperative dental and skeletal relapses in patients undergoing orthognathic surgery for skeletal class III deformity. The surgical interventions were single-jaw versus double-jaw procedures. Twenty-four adult patients with skeletal class III deformity presented with functional and esthetic problems. Patients were randomized to receive single-...

article

Optical coherence tomography in the assessment of suspicious oral lesions: An immediate ex vivo study

Zaid Hamdoon, Waseem Jerjes, Tahwinder Upile, Gordon McKenzie, more

Photodiagnosis and Photodynamic Therapy > 2013 > 10 > 1 > 17-27

Optical coherence tomography (OCT) is an evolving optical technology that is capable of delivering real-time, high-resolution signatures of tissue.The purpose of this immediate ex vivo prospective clinical study was: (1) to assess the sensitivity and specificity of OCT on biopsy material in identifying potentially malignant and malignant oral lesions, (2) to determine the inter-observer agreement...

article

CO₂ laser of oral dysplasia: clinicopathological features of recurrence and malignant transformation

Waseem Jerjes, Tahwinder Upile, Zaid Hamdoon, Mohammed Al-Khawalde, more

Lasers in Medical Science > 2012 > 27 > 1 > 169-179

The use of the CO₂ laser in the management of oral dysplastic lesions has become a more common practice. Very few studies have evaluated recurrence, residual disease malignant transformation, and overall outcome in patients undergoing such a procedure. In this prospective study, a total of 123 oral dysplastic lesions from 77 consecutive patients were treated with the CO₂ laser (resection and/or ablation)...

article

Prospective evaluation of 110 patients following ultrasound-guided photodynamic therapy for deep seated pathologies

Waseem Jerjes, Tahwinder Upile, Charles Alexander Mosse, Zaid Hamdoon, more

Photodiagnosis and Photodynamic Therapy > 2011 > 8 > 4 > 297-306

Photodynamic therapy, the fourth oncological interventional modality has proved its success in the management of variety of pathologies involving the human body. Our aim in this prospective clinical study was to continue evaluating the outcome following ultrasound-guided interstitial PDT of pathologies involving the human body. Patients’ reports on quality of life with clinical and radiological evaluation...

article

Prospective evaluation of outcome after transoral CO2 laser resection of T1/T2 oral squamous cell carcinoma

Waseem Jerjes, Tahwinder Upile, Zaid Hamdoon, Charles Alexannder Mosse, more

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology > 2011 > 112 > 2 > 180-187

Oral cancer is the sixth most common cancer in the world. The incidence of oral squamous cell carcinoma (OSCC) continues to be high, if not increasing. This prospective study assessed the oncological outcomes following transoral CO ₂ laser resection of T1/T2 N0 OSCC. Patients' 3-year disease-specific survival and disease-free survival were evaluated.The patients' data included a range of clinical,...

article

Photodynamic therapy outcome for T1/T2 N0 oral squamous cell carcinoma

Waseem Jerjes, Tahwinder Upile, Zaid Hamdoon, Charles Alexander Mosse, more

Lasers in Surgery and Medicine > 43 > 6 > 463 - 469

IntroductionThis new prospective clinical study assessed the oncological outcomes following surface illumination mTHPC‐photodynamic therapy of T1/T2 N0 oral squamous cell carcinoma (OSCC) patients. Material/MethodsThirty‐eight patients participated in this study. Their mean age at the first diagnosis of OSCC was 58.0 years. Common clinical presentation was an ulcer mainly identified in the tongue,...

article

Interstitial PDT for vascular anomalies

Waseem Jerjes, Tahwinder Upile, Zaid Hamdoon, Charles Alexander Mosse, more

Lasers in Surgery and Medicine > 43 > 5 > 357 - 365

IntroductionPhotodynamic therapy is a proven therapeutic modality in the management of variety of pathologies involving the human body. Our aim in this clinical study is to prospectively evaluate the outcome following interstitial photodynamic therapy for patients with vascular anomalies. Patients' reports on quality of life with clinical and radiological evaluation were the main end point parameters...

article

Photodynamic therapy: The minimally invasive surgical intervention for advanced and/or recurrent tongue base carcinoma

Waseem Jerjes, Tahwinder Upile, Zaid Hamdoon, Syedda Abbas, more

Lasers in Surgery and Medicine > 43 > 4 > 283 - 292

IntroductionThe management of tongue base carcinoma continues to be a major challenge in head and neck oncology. Our aim in this prospective study was to evaluate the outcome following ultrasound‐guided interstitial photodynamic therapy (US‐iPDT) of stage IV tongue base carcinoma patients. Patients' reports on quality of life with clinical and radiological evaluation were the main end point parameters...

article

Photodynamic therapy outcome for oral dysplasia

Waseem Jerjes, Tahwinder Upile, Zaid Hamdoon, Charles Alexander Mosse, more

Lasers in Surgery and Medicine > 43 > 3 > 192 - 199

IntroductionPhotodynamic therapy (PDT) is a minimally invasive surgical intervention used in the management of tissue disorders. It can be applied before, or after, any of the conventional modalities, without compromising these treatments or being compromised itself. Materials and MethodsIn this prospective study, a total of 147 consecutive patients with oral potentially malignant disorders were...

article

Optical coherence tomography-guided photodynamic therapy for skin cancer: Case study

Zaid Hamdoon, Waseem Jerjes, Tahwinder Upile, Colin Hopper

Photodiagnosis and Photodynamic Therapy > 2011 > 8 > 1 > 49-52

Photodynamic therapy (PDT) has been identified as a successful therapy for skin cancer. This case study investigates the role of optical coherence tomography (OCT) in lesion (squamous cell carcinoma) mapping, assisting the surgeon to correctly deliver PDT and monitor the outcome. Optical coherence tomographic images were acquired pre-treatment to assess tumour extent and margins to enable guidance...

article

Adenoid cystic carcinoma of the tongue base treated with ultrasound-guided interstitial photodynamic therapy: A case study

Jonas Osher, Waseem Jerjes, Tahwinder Upile, Zaid Hamdoon, more

Photodiagnosis and Photodynamic Therapy > 2011 > 8 > 1 > 68-71

Adenoid cystic carcinoma is a malignant neoplasm arising from the salivary glands. It accounts for 10-15% of all salivary gland neoplasms, representing 1-2% of malignant neoplasms of the head and neck. It is characterized by slow growth, diffuse invasion and potential to produce distant metastases, mainly to the lungs and bone. We present a case of adenoid cystic carcinoma of the base of tongue treated...

article

Subglottic carcinoma treated with surgery and adjuvant photodynamic therapy

Farai Nhembe, Waseem Jerjes, Tahwinder Upile, Zaid Hamdoon, more

Photodiagnosis and Photodynamic Therapy > 2010 > 7 > 4 > 284-287

Subglottic cancers are extremely rare as a primary malignancy representing <8% of all laryngeal cancers. Typical age at presentation is in the 5th decade. There are three main types of subglottic carcinoma: adenocarcinoma, mucoepidermoid and adenoid cystic carcinoma. We present a rare case of subglottic cancer treated with surgery and adjuvant photodynamic therapy.

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Keywords

PHOTODYNAMIC THERAPY (12)
OPTICAL COHERENCE TOMOGRAPHY (5)
RECURRENCE (4)
SKIN CANCER (4)
MTHPC (3)
ORAL CANCER (3)
ORAL DYSPLASIA (3)
BASAL CELL CARCINOMA (2)
MAL (2)
NMSC (2)
OPTICAL BIOPSY (2)
OPTICAL DIAGNOSTICS (2)
ORAL POTENTIALLY MALIGNANT DISORDERS (2)
PDT (2)
SQUAMOUS CELL CARCINOMA (2)
5-ALA (1)
5‐ALA (1)
ACTINIC KERATOSIS (1)
ADENOID CYSTIC CARCINOMA (1)
ADJUVANT PHOTODYNAMIC THERAPY (1)
ALLEVIATE SYMPTOMS (1)
CANCER (1)
CASE SERIES (1)
CEMENTUM DAMAGE (1)
CHONDROSARCOMA (1)
CLINICOPATHOLOGICAL FEATURES (1)
CO2 LASER (1)
DENTAL IMPLANT (1)
DISEASE CONTROL (1)
EPITHELIAL THICKNESS (1)
ERYTHROPLAKIA (1)
HEAD AND NECK (1)
HEAD AND NECK SURGERY (1)
HYOID (1)
INTERFEROMETRIC TOMOGRAPHIC IMAGING (1)
INTERSTITIAL (1)
INTERSTITIAL PDT (1)
LACRIMAL GLAND (1)
LEUKOPLAKIA (1)
MALIGNANT TRANSFORMATION (1)
MANTLE CELL LYMPHOMA (1)
METASTATIC (1)
MINIMALLY INVASIVE SURGERY (1)
MORBIDITY (1)
MORTALITY (1)
NON-HODGKIN LYMPHOMA (1)
OCT (1)
ONCOLOGY (1)
ORAL LESIONS (1)
ORAL SQUAMOUS CELL CARCINOMA (1)
OROFACIAL REGION (1)
PERICAROTID MALIGNANCY (1)
PERIORBITAL SKIN CANCERS (1)
PRE-CANCER (1)
RENAL CELL CARCINOMA (1)
RESECTION MARGINS (1)
ROOT INJURY (1)
ROOT PERFORATION (1)
SENSITIVITY (1)
SPECIFICITY (1)
STENTING (1)
SUBGLOTTIC CARCINOMA (1)
SWEPT-SOURCE FOURIER-DOMAIN OCT (1)
T1/T2 ORAL CANCER (1)
TONGUE BASE (1)
TONGUE BASE CARCINOMA (1)
ULTRASOUND-GUIDED (1)
US-GUIDED (1)
VASCULAR ANOMALIES (1)
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Elsevier (20)
Wiley (8)
Springer (1)

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Search results for: Zaid Hamdoon

The consequences and outcomes associated with dental implants encroaching on adjacent teeth

Apparent Complete Response of a Treatment Refractory and Recurrent Squamous Cell Carcinoma Lesion to Photochemical Internalization: A Clinical Case Study

Periorbital skin cancers subjected to mTHPC‐photodynamic therapy: A prospective study

Structural validation of facial skin using optical coherence tomography: A descriptive study

Photodynamic therapy in the management of basal cell carcinoma: Retrospective evaluation of outcome

Photodynamic therapy in the management of actinic keratosis: Retrospective evaluation of outcome

Disulfonated tetraphenyl chlorin (TPCS2a)-induced photochemical internalisation of bleomycin in patients with solid malignancies: a phase 1, dose-escalation, first-in-man trial

Optical coherence tomography in the assessment of oral squamous cell carcinoma resection margins

Skeletal and dental relapses after skeletal class III deformity correction surgery: single-jaw versus double-jaw procedures

Optical coherence tomography in the assessment of suspicious oral lesions: An immediate ex vivo study

CO₂ laser of oral dysplasia: clinicopathological features of recurrence and malignant transformation

Prospective evaluation of 110 patients following ultrasound-guided photodynamic therapy for deep seated pathologies

Prospective evaluation of outcome after transoral CO2 laser resection of T1/T2 oral squamous cell carcinoma

Photodynamic therapy outcome for T1/T2 N0 oral squamous cell carcinoma

Interstitial PDT for vascular anomalies

Photodynamic therapy: The minimally invasive surgical intervention for advanced and/or recurrent tongue base carcinoma

Photodynamic therapy outcome for oral dysplasia

Optical coherence tomography-guided photodynamic therapy for skin cancer: Case study

Adenoid cystic carcinoma of the tongue base treated with ultrasound-guided interstitial photodynamic therapy: A case study

Subglottic carcinoma treated with surgery and adjuvant photodynamic therapy

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