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Previously paper had demonstrated the effect of rheam palmatum against herpes simplex virus (HSV) in vitro(Luo J et al, J Natl Infect Dis, 1991). In order to confirm the therapeutic effect of rheum palmatum in herpes simplex virus infection in mice. Animial model of herpetic encephalitis was used to demonstrated the pontential of rheum palmatum. The mice were treated subcutaneously with rheum palmatum...