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Juvenile myelomonocytic leukemia (JMML), previously known as juvenile chronic myeloid leukemia (JCML), is a rare, myelodysplastic-myeloproliferative disease typically presenting in early childhood. This disorder is difficult to distinguish from other myeloproliferative syndromes such as chronic myeloid leukemia (CML) because of the similarities in their clinical and bone marrow findings. However,...
Nous rapportons l’observation d’un nouveau-né qui a présenté dès les premières heures de vie une anémie hémolytique avec présence de schizocytes sur le frottis sanguin, thrombopénie, hyperbilirubinémie et insuffisance rénale aiguë. L’évolution a été favorable grâce à la mise en route rapide d’une plasmathérapie. Le dosage de la protéase de clivage du facteur de von Willebrand (métallo-protéase ADAMTS...
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