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There is a continuous demand for preclinical modeling of the interaction of dendritic cells with the immune system and cancer cells. Recent progress in gene expression profiling with nucleic acid microarrays, in silico modeling and in vivo cell and animal approaches for non-clinical proof of safety and efficacy of these immunotherapies is summarized. Immunoinformatic approaches look promising to unfold...
Based on the results of in vitro-experiments in practically estrogen-free media and in the absence of estrogen-beta receptors, soy isoflavones have been suspected to enhance proliferation of MCF-7 breast cancer cells. In this study the effects of soy isoflavones on MCF-7 cells were investigated in the presence and absence of estrogen, directly and in a metabolized form by testing sera of postmenopausal...
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