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The natural production of patchouli oil in developing countries cannot meet the increasing demand any more. This leads to socioecological consequences, such as the use of arable land, which is actually intended for food. Hence, the world market price increased up to $150/kg. An alternative is the biotechnological production of patchouli oil using a multiproduct sesquiterpene synthase, the patchoulol...
The application of enzyme thermistor devices for the continuous monitoring of enzymatic processes is described. Different hardware concepts are presented and discussed, practical results are also given. These devices were used to analyze the enantiomeric excess in biotransformation processes and for thermal immunoanalysis. In addition, the biosensors were applied for the monitoring and control of...
A flow injection analysis system for on-line monitoring of enzyme-catalyzed l-ornithine, l-methionine, and fructose synthesis is presented. An enzyme thermistor was used as detector. The enzyme-catalyzed reactions were performed in a simple batch reactor with immobilized biocatalysts (arginase, acylase, invertase, or glucose isomerase, respectively). The bioreactor was connected with a computer-controlled...
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