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The drug acetazolamide (C 4 H 6 N 4 O 3 S 2 ) was studied using a simultaneous thermogravimetric-differential thermal analysis (TG-DTA) unit. The study covered the temperature range of ambient to 600 o C. The DTA showed a melting point of 258.5 o C followed by a three-stage decomposition. The TG-DTG plots clearly show the decomposition when subjected...
Allopurinol sublimates when subjected to thermogravimetry in a nitrogen atmosphere. The process is zero order and plots of lnk versus reciprocal temperature (K) give a value of 132.64kJmol -1 for the activation energy. On the basis that equilibrium is achieved at all temperatures the data is used to establish a plot of the vapor pressure curve versus temperature from which a Clausius-Clapeyron...
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