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A lattice random-walk model is used to simulate diffusion in a porous polymer. This model may be useful for the practical design of drug-release systems. Both interacting and noninteracting particles (random walkers) were allowed to diffuse through a pore with a single exit hole. It was found that the specific interactions among the diffusing particles have little influence on the overall release...
A one-dimensional kinetic Ising model is developed to describe the binding of myosin subfragment 1 (SF-1) to regulated actin. The model allows for cooperative interactions between individual actin sites with bound SF-1 ligands rather than assuming that groups of actin monomer sites change their state in a cooperative fashion. With the triplet closure approximation, the model yields a set of 16 independent...