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Morphological, cultural, and immuno-histochemical characteristics of “Nanobacterium sanguineum” (NB) described in the literature are reviewed. NB is reported to be a motile, Gram negative organism that divides by binary fission within a calcium-coated slimy shell; this yeast-like shell replicates by budding. It measures between 20 and 200nm with a unique structure containing 16S ribosomal RNA. NB...
In vitro inactivation of cell-free human immunodeficiency virus (CFHIV) was investigated by mixing replication-competent virions with aliquots of a culture medium (RPMI) containing increasing amounts (62.5-500 μg/ml) of ascorbic acid (AA) at pH7. Similarly, mixtures of CFHIV and 500 μg/ml AA in whole blood (WB) and leukocyte depleted blood (LDB) were made; control mixtures containing either CFHIV...
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