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Glioblastoma multiforme (GBM), a malignant brain tumor, frequently exploit microvessels as guides for migration. Understanding cell-cell interaction between vascular cells and GBM cells may suggest a new therapeutic direction. We developed physiological 3-D glioma-vascular niche model to investigate this cell-cell interaction using 3-D bioprinting technology. In the model, patient-derived GBM cell...
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