Seo Young Shin

article

Synthesis of aminoalkyl-substituted aurone derivatives as acetylcholinesterase inhibitors

Young Hun Lee, Min Cheol Shin, Yong Don Yun, Seo Young Shin, more

Bioorganic & Medicinal Chemistry > 2015 > 23 > 1 > 231-240

Alzheimer’s disease (AD), a progressive and neurodegenerative disorder of the brain, is the most common cause of dementia among elderly people. To date, the successful therapeutic strategy to treat AD is maintaining the levels of acetylcholine by inhibiting acetylcholinesterase (AChE). In the present study, aurone derivatives were designed and synthesized as AChE inhibitors based on the lead structure...

article

SIRT1 activation by methylene blue, a repurposed drug, leads to AMPK-mediated inhibition of steatosis and steatohepatitis

Seo Young Shin, Tae Hyun Kim, Hongmin Wu, Young Hee Choi, more

European Journal of Pharmacology > 2014 > 727 > Complete > 115-124

Sirtuins maintain energy balance. Particularly, sirtuin 1 (SIRT1) activation mimics calorie restriction and nutrient utilization. However, no medications are available for the up-regulation of SIRT1. Methylene blue (MB) had been in clinical trials for the treatment of neurological diseases. This study investigated the effect of MB on sirtuin expression in association with the treatment of steatosis...

article

Synthesis of aurones and their inhibitory effects on nitric oxide and PGE2 productions in LPS-induced RAW 264.7 cells

Seo Young Shin, Min Cheol Shin, Ji-Sun Shin, Kyung-Tae Lee, more

Bioorganic & Medicinal Chemistry Letters > 2011 > 21 > 15 > 4520-4523

Sulfuretin is one of major constituents of Rhus verniciflua that exerts anti-inflammatory activities. Some of aurones were synthesized as sulfuretin derivatives and evaluated for their abilities to inhibit NO and PGE ₂ production in LPS-induced RAW 264.7 cells in order to reveal the relationship. Of the aurones synthesized in the present study, 2h and 2i, which possess C-6 hydroxyl group in...

article

Key attributes of internal service recovery strategies as perceived by frontline food service employees

Joanne Jung-Eun Yoo, Seo-Young Shin, Il-Sun Yang

International Journal of Hospitality Management > 2006 > 25 > 3 > 496-509

This paper reports on a study investigating key attributes of internal service recovery strategies from the perspectives of frontline food service employees in restaurants. Insights into the employees’ perceived importance of different attributes were obtained through the use of conjoint analysis. The study examined how customer-contact employees evaluate internal service recovery strategies, and...

INFONA - science communication portal

Search results for: Seo Young Shin

Synthesis of aminoalkyl-substituted aurone derivatives as acetylcholinesterase inhibitors

SIRT1 activation by methylene blue, a repurposed drug, leads to AMPK-mediated inhibition of steatosis and steatohepatitis

Synthesis of aurones and their inhibitory effects on nitric oxide and PGE2 productions in LPS-induced RAW 264.7 cells

Key attributes of internal service recovery strategies as perceived by frontline food service employees

Filter options

Publication date

Keywords

Journal

INFONA - science communication portal

Search results for: Seo Young Shin

Synthesis of aminoalkyl-substituted aurone derivatives as acetylcholinesterase inhibitors

SIRT1 activation by methylene blue, a repurposed drug, leads to AMPK-mediated inhibition of steatosis and steatohepatitis

Synthesis of aurones and their inhibitory effects on nitric oxide and PGE2 productions in LPS-induced RAW 264.7 cells

Key attributes of internal service recovery strategies as perceived by frontline food service employees

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Keywords

Journal

Reporting an error / abuse

Sending the report failed

Accessibility options