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Coronary heart disease (CHD) is the leading cause of mortality worldwide. CHD clusters in families but this familial aggregation remains largely unexplained. ESR1 is a candidate gene for CHD although recent meta-analyses of the rs2234693 variant reported inconsistent evidence for association with myocardial infarction (MI) in men. The objectives of this study were to perform a qualitative and a quantitative...
A cross-sectional study was conducted in the Spanish European Prospective Investigation into Cancer and Nutrition (EPIC) cohort to investigate the association among education level, as a measurement of socioeconomic position, gender, and dietary nutrient intake, focusing on plant sterols, in a Mediterranean population.A sample of 25 615 women and 15 552 men (29–69 y old) from the Spanish EPIC cohort...
Background Phytosterols in natural foods are thought to inhibit cholesterol absorption. The Mediterranean diet is rich in phytosterol-containing plant foods. Aim of the study To assess whether increasing phytosterol intake from natural foods was associated with a cholesterol-lowering effect in a substudy of a randomized trial of nutritional intervention with Mediterranean diets for primary cardiovascular...
Background Phytosterols in natural foods are thought to inhibit cholesterol absorption. The Mediterranean diet is rich in phytosterol-containing plant foods. Aim of the study To assess whether increasing phytosterol intake from natural foods was associated with a cholesterol-lowering effect in a substudy of a randomized trial of nutritional intervention with Mediterranean diets for primary cardiovascular...
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