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Medical decision support tools are not widely used by clinicians, perhaps because most do not explain the decisions. We describe an approach for case-based systems using automated pattern recognition techniques. Multivariate methods estimate the degree of similarity between a new case and those in the database, and graphical displays allow users to combine this information with their own expertise...
There is currently no widely recognised methodology for undertaking data quality assessment in electronic health records used for research. In an attempt to address this, we have developed a protocol for measuring and monitoring data quality in primary care research databases, whereby practice-based data quality measures are tailored to the intended use of the data. Our approach was informed by an...
Primary care research databases provide a significant resource for health services and epidemiological research. However since data are recorded primarily for clinical care their suitability for research may vary widely according to the research application or recording practices of individual general practitioners. A methodological approach for characterising data quality is required. We describe...
Concerns have been raised about the mental and physical health of UK military personnel who deployed to the 2003 war in Iraq and subsequent tours of duty in the country. We compared health outcomes in a random sample of UK armed forces personnel who were deployed to the 2003 Iraq war with those in personnel who were not deployed. Participants completed a questionnaire covering the nature of the...
An exploratory statistical analysis has been undertaken of 640 1 H NMR spectra of rat urine, obtained from predose and control animals during the course of eight separate toxicology studies. The aim was to determine the degree and type of variation between 1 H NMR spectra from such control animals and to investigate the variations in the spectral descriptors based on averaged peak...
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