The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Commitment of the germ cell lineage during embryogenesis depends on zygotic gene expression in mammals, but little is known about the signaling molecules required for germ cell formation. Here we show that the intracellular signaling molecule SMAD1, acting downstream of bone morphogenetic protein (BMP) receptors, is required for the commitment of germ cell lineage from epiblast in early mouse embryos...
An alternative stereoselective synthesis of 9-(6,7-dideoxy-β-d-allo-hept-5-ynofuranosy)adenine is described, which makes use of stereoselective reduction of methyl 5-C-trimethylsilylethynyl-5-oxo-2,3-di-O-tert-butyldimethylsilyl-β-d-ribofu ranoside (4), followed by glycosidation with N 6 -benzoyladenine. It was revealed that sugar puckering of the furanose ring and steric hindrance of the...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.