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High-frequency ultrasound (>20 MHz) imaging has gained widespread attention due to its high spatial resolution being useful for basic cardiovascular and cancer research involving small animals. The sampling rate of the analog-to-digital converter in a high-frequency ultrasound system usually needs to be higher than 120-MHz to satisfy the Nyquist requirement. However, the sampling rate is typically...
Super resolution localization microscopy (SRLM) techniques such as STORM and PALM overcome the ∼200nm diffraction limit of conventional light microscopy by randomly activating separate fluorophores over time and computationally aggregating their nanometer resolution detected locations for image reconstruction. However, a basic limitation of current SRLM approaches for live cell imaging is their low...
We evaluated the performance of a position-sensitive virtual Frisch-grid (VFG) CdZnTe detector, , via sensing strips on its side surfaces. Once the signals were collected from the anode, and from four or eight strips attached to the detector’s sides, we assessed the anode’s energy spectra and derived histograms from the side electrodes to evaluate...
The goal of our study was twofold: To determine the distribution of signals in position-sensitive CdZnTe (CZT)-based virtual Frisch-grid detectors (VFGDs) with side-sensing pads, and to evaluate the feasibility of accurately measuring the X- and Y-coordinates where a photon interaction occurs within a single VFGD module. Accordingly, we collected signals from an anode, and from four or eight sensing...
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