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The cell adhesion strength between FN and the living cell was successfully examined using an AFM cantilever having a FN-coated spherical microbead as a probe. The microbead was used to increase (by some 55-fold) the area of contact with the cell surface. Fibronectin (FN) was chosen as the ligand and immobilized on the bead. The area under the force-extension curve obtained during retraction of the...