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Improving accuracy of the available predictive DNA methods is important for their wider use in routine forensic work. Information on age in the process of identification of an unknown individual may provide important hints that can speed up the process of investigation. DNA methylation markers have been demonstrated to provide accurate age estimation in forensics, but there is growing evidence that...
IFN-α signals through the Jak-STAT pathway to induce expression of IFN-stimulated genes (ISGs) with antiviral functions. USP18 is an IFN-inducible negative regulator of the Jak-STAT pathway. Upregulation of USP18 results in a long-lasting desensitization of IFN-α signalling. As a result of this IFN-induced refractoriness, ISG levels decrease back to baseline despite continuous presence of the cytokine...
Three methods of cryopreservation: vitrification, encapsulation and slow freezing were discussed. The factors having influence on long-term storage in liquid nitrogen as selection of plant explants, media, optimal condition for regeneration and growth of plants were described. Practical utilisation of vitrification method and obtained results on garlic (Allium sativum L.) are given as an example....
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