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Chemokines and their receptors participate in pathomechanism of bronchial asthma.The aim of the study was to analyze the pattern of chemokine receptor expression on T cells in severe asthmatics and to compare to mild-to-moderate patients and controls.Flow cytometric analysis of CXCR1, CXCR2, CXCR3, CCR3, CCR4, CCR5, CCR7, CCR8 expression on CD3+CD8− and CD3+CD8+ cells was performed in patients with...
Dzieci chorujące na nawracające zakażenia układu oddechowego powinny mieć wykonane badania przesiewowe w kierunku zaburzeń odporności. Niektóre zaburzenia odporności wiążą się z częstszym występowaniem alergii.Celem badania była retrospektywna analiza występowania zaburzeń odporności typu humoralnego i atopowych chorób alergicznych wśród dzieci z nawracającymi zakażeniami układu oddechowego.Badaniem...
T helper subset dysregulation is evident in allergic disorders. The role of T cytotoxic subsets is less understood. We investigated whether allergen immunotherapy in intermittent allergic rhinitis influences the intracellular expression of IL-4 and IFN-gamma by CD3 + CD8 − and CD3 + CD8 + cells.Nineteen adult patients with intermittent allergic rhinitis were evaluated...
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