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Background
Colonic transit measurement [geometric center (GC) at 24 and 48 hours] identifies slow transit constipation (STC) in patients with chronic constipation.
Aim
To evaluate the utility of the difference between GC24 and GC48 (Δ48‐24) to identify STC in adults with chronic constipation.
Methods
We reviewed medical records of 250 patients, aged 18‐75 years, who underwent colonic transit...
Glaucoma results in decline and loss of retinal ganglion cells (RGCs), and is associated with microglia and complement activation, with correlation between early microgliosis in the optic nerve head and later optic nerve pathology. Inhibiting microglia activation can protect RGC axons, implicating microglia in glaucoma pathogenesis. Thus, microglia and innate neuroimmune events are critical components...
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