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Objectives
No individual homocysteine (Hcy) metabolite has been studied as a risk marker for coronary artery disease (CAD). Our objective was to examine Hcy‐thiolactone, a chemically reactive metabolite generated by methionyl‐tRNA synthetase and cleared by the kidney, as a risk predictor of incident acute myocardial infarction (AMI) in the Western Norway B‐Vitamin Intervention Trial.
Design
Single...
Derywatyzacja chemiczna od szeregu lat stanowi nieodzowny etap wielu procedur analitycznych, pomimo nieustannego doskonalenia przyrządów pomiarowych oraz rozwoju metod opartych na coraz bardziej wyrafinowanych technikach instrumentalnych.
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