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Background. Caloric restriction (CR) leads to decrease metabolic intensity, which results in a reduction of oxygen consumption and the amount of free radicals. This can affect the function of the liver. Studies show that caloric restriction does not alter or significantly increase the enzyme activity associated with gluconeogenesis, but the effect was different according to the age of the model animals...
Background. Nutritional recommendations emphasize the need to limit consumption of saturated fatty acids and to increase the intake of polyunsaturated fatty acids in the prevention of non-communicable chronic diseases, particularly cardiovascular diseases. Among the fatty acids with health-related effects on the body, conjugated fatty acids are mentioned (i.e. CLA). Objective. The current study was...
In Poland, a high level of nitrate and nitrite in food and iodine deficiency have been observed in the last years. The effects of potential goitrogens, namely allylisothiocyanate (SCN-), nitrate (NO3 -) and nitrite (NO2 -) on growth performance, serum hormones (fT4, TSH) and thyroid morphology were investigated in rats. Simultaneously, the potential antigoitrogenic effects of iodine and selenium supplements...
Extensive research have indicated that commercial conjugated linoleic acid (CLA), fed to laboratory animals, showed several health-related properties. The objective of this study was to assess the effect of CLA on serum lipid profile, plasma malondialdehyde and liver fatty acids profile in Wistar rats fed for 23 d. The experimental diets were: I-AIN-93G - control (C), II- AIN-93G diet + 1.0% CLA....
The objectives of the present study were to estimate the effects of increasing levels of the dietary intake of nitrites on: (1) urinary iodine excretion, 2) changes in the morphology of thyroid follicles, and 3) thyroid gland hormonegenesis, in laboratory rats. Effects of nitrites on serum lipoproteins were examined as well. Feeding graded amounts of nitrites to rats resulted in: (1) decreased iodine...
The effect of increasing levels of sodium nitrate on urinary iodine excretion, changes in the morphology of thyroid follicles, and thyroid gland hormonogenesis were studied. In addition, effects of nitrates on serum lipoproteins were examined. Twenty-four, 5-week old, growing male rats of Wistar strain were randomly assigned to four experimental groups (I – 0, II – 500, III – 1500, and IV – 3000 mg...
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