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The investigations carried out in the Institute of Industrial Organic Chemistry on sulphur fungicides are discussed and some neu investigation possibilities are presented. Elementary sulphur - one of the oldest known fungicide is still being used in plant protection, mostly against powdery mildews in orchard, vegetables, ornamental and cereal crops. Because it is of low toxicity to mammals and aqueous...
The synthesis methods of some new compounds from the group of the acrylonitrile methylothio derivatives were described, especially the synthesis of 2-methylothio-2-amine-1-cyanoacrylonitrile. The main substrate for the synthesis was malononitrile. They demonstrate fungicidal activity against five fungi. They possessed however also negative properties: mammal toxicicity and high allergenic activity.
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