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Proteoglycans can be found in the extracellular matrix of most tissues. They play the role of receptors, take part in cellular adhesion and also interactions between cells. Proteoglycans consist of proteins with one or more covalently bonded glycosaminoglycans. There are seven different types of glycosaminoglycans: hyaluronic acid, heparin and sulphates of chondroitin, keratan I and II, heparin and...
The objective of this study was to examine the feasibility of identification and selection of cattle embryos based on green fluorescence (GFP-positive) in order to obtain calves carrying an integrated transgene. The construct used (pbLGTNF-EGFP) contained the human tumor necrosis factor alpha (hTNFa) gene fused to the bovine betalactoglobulin promoter (bLG) in plasm id vector pCX-EGFP. In four experiments,...
W Polsce i na świecie próchnica została uznana za chorobę społeczną. Badania z udziałem ludzi potwierdziły, że za inicjację i postępowanie tej choroby odpowiedzialne są bakterie Streptococcus mutans. Wiele analiz wskazuje na kluczową rolę specyficznych białek S. mutans (antygen 1/11, glukozylotrasferaza GTF, białka GBP) w patogenezie próchnicy. Badania dowiodły, że antygeny te bądź ich fragmenty mogą...
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