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Male Wistar rats on a standard or vitamin C or selenium supplemented diet received orally a solution of cadmium chloride at a dose corresponding to 10 mg of cadmium/kg of diet. Rats were killed within 28 days of cadmium administration. Results showed that the cadmium intoxication decreased renal and hepatic superoxide dismutase (SOD) activity on day 7 and increased on days 14, 21 and 28. Rats fed...
Male Wistar rats received orally a solution of cadmium chloride at a dose corresponding to 10 mg of cadmium/kg of diet. Rats were killed at 7, 14, 21 and 28 days of cadmium administration and 7 days postdosing. Results showed that the cadmium intoxication affected renal and hepatic glutathione content and superoxide dismutase in a dose-dependent manner. Changes in glutathione S-transferase activity...
We have reviewed available data from our and other laboratories relevant to the effects of single and repeated intoxication with mercury on the metabolism of several elements in animal bodies. Additionally, emphasis has been placed on the influence of zinc and selenium on mercury toxicity. The data indicate that mercuric chloride and methyl mercury affect quite differently the distribution pattern...
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