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Host immunosuppression occurs during chronic nematode infection, partly due to effector T‐cell hyporesponsiveness. The role of P‐glycoprotein (P‐gp), a member of the ABC transporter family, has been assessed in T‐cell activity. This study assesses the possible role of P‐gp in T‐cell activity during nematode infection. Our findings indicate that blockade of P‐gp in vivo increased protection against...
It is estimated that more than half of the nowadays known species are pathogenic parasites. Among macroparasites gastrointestinal nematodes are one of most common and having significant impact on life and health. Those organisms reveal strong, specific immune response in host, involving primary mechanisms associated with regulatory and Th2 cells. Referring to immunomodulatory abilities of helminths,...
Osteoarthritis (OA) is among the five most disabling diseases. Aims of this study were to review treatment options for patients suffering hip or knee osteoarthritis and to assess patients' attitudes toward telerehabilitation over the Internet at the beginning of practical implementation of telerehabilitation platform. The study group consisted of hip osteoarthritis patients at the end stage of their...
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