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We performed Killer cell immunoglobulin‐like receptor (KIR) genotyping on 1271 individuals of Chinese Han origin including 102 families and 965 unrelated individuals. The families (with one child and both parents) were subjected for haplotype analysis. Forty‐one different genotypes were identified. The frequencies of the KIR genotypes found in the family panel were confirmed by those found in the...
A novel HLA‐C*01 variant allele differs from the closest allele C*01:02:01 by single nucleotide change at coding sequence nt 316 C>T (codon 82 CGC>TGC) in exon 2, which causes an amino acid change Arg82Cys.
The novel HLA‐C*01:38 variant allele differs from the closest allele C*01:02:01 by a single nucleotide change at coding sequence (CDS) nt 430 G>A (codon 120 GGC>AGC) in exon 3, which causes an amino acid change Gly120Ser.
The novel human leukocyte antigen (HLA)‐Cw*075602 variant allele differs from the closest allele Cw*07020101 by a single nucleotide change at genomic DNA nt 473 G > C (CDS nt 343 G > C , codon 91 GGG > CGG ) in exon 2, which results in an amino acid change Gly91Arg.
Genomic full‐length sequence of human leukocyte antigen (HLA)‐Cw*0706, differing from its closet allele Cw*070 101 by six nucleotide exchanges, was detected in two Chinese individuals.
A novel HLA‐Cw*0624 variant allele differs from the closest allele Cw*06020101 by single nucleotide change at genomic nt 923 T>C (CDS nt 547 T>C, codon 159 TAC>CAC) in exon 3, which results in an amino acid change Tyr159His.
A novel HLA‐C allele, Cw*0824, which was identified from an individual of the Han Chinese, differs from Cw*080101 at codon 222 (GAG > AAG ) in exon 4, which results in an amino acid change Glu222Lys.
In recent years, many human leukocyte antigen (HLA)‐C alleles have been identified. Up to date, 23 different Cw*08 alleles have been identified according to the IMGT/HLA Database release 2.25.2 May...
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