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Cancer and Cardiovascular diseases (CVD) are the two most prominent causes of death worldwide. Emerging evidence indicates shared risk factors and a common biology between these diseases. For instance, chronic inflammation has a significant role in contributing to both diseases. An alteration of the vasculature and the endothelial cells plays a key role in pathogenesis of CVD and cancer. The widespread...
Vascular progenitor cells contribute to repair of injured vasculature. In this study, we aimed to investigate the role of bone marrow–derived cells in the intimal formation after arterial injury.Balloon injury of the femoral artery of wild-type mice was followed by local delivery of bone marrow–derived cells from GFP transgenic mice. The arteries were collected 1, 4, 7, and 14 days after injury and...
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