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Paired-pulse stimulation is a standard protocol that has been used for decades to characterize dynamic systems: the differences in responses to two sequential identical stimuli as a function of inter-stimulus interval provide quantitative information on the dynamics of the system. In neuroscience, the paired-pulse protocol is also widely used at multiple levels of analysis, from behavioral conditioning...
This paper introduces a new time-frequency coherence analysis method based on Lomb periodogram and applies it to investigate the time-varying synchronization of multi-channel event-related potentials (ERP). The Lomb periodogram is first extended to a time-frequency analysis method by windowing the observation. Furthermore, the window bandwidth is selected adaptively by the intersection of confidence...
Degenerative chronic spinal cord compression induced cervical myelopathy is a common cause of spinal cord dysfunction. The disease generally leads to impairment of the sensory and motor function of the cord progressively and insidiously. However, the underlying pathophysiology and the precise mechanism of the disease are still uncertain and remain to be investigated. The establishment of an animal...
This paper undertakes a comparative study of adaptive signal enhancers (ASE) of somatosensory evoked potentials (SEP) for spinal cord compression detection. We compare the ASE methods based on two adaptive filtering algorithms: the least mean squares (LMS) and Kalman filter (KF) in terms of their convergence rate, variability, and complexity. In addition, the two ASE methods are compared with the...
Measurement of human spinal profile is useful in spinal deformation detection and ergonomic investigation. Usually, the measurement is based on radiological test, which is in company with invasive radiation. This paper proposes a quantitative, objective measurement method by means of stereo vision. While measuring, markers having three different colors, red, green, and blue, are sequentially adhered...
The control of neuron position and orienting axon outgrowth is a significant focus in the development of cell biosensors and the study of neural regeneration. During the development, neurons communicate with each other by growing out axons and dendrites to form network. For the central nerve system: brain and spinal cord, which are very limited in their ability to repair. A better resolution for the...
The protocol for spinal DTI and tractography with high SNR and spatial resolution has been developed and tested on 6 healthy subjects and 1 CSM patient in a 3T system. Fiber bundles were traced and were found running parallel to the cervical spinal cord correlating with the neuronal anatomy in normal subjects. The FA maps showed consistent low FA region connecting all spinal levels, which corresponded...
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