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Scope
The polyphenol xanthohumol (XN) improves dysfunctional glucose and lipid metabolism in diet‐induced obesity animal models. Because XN changes intestinal microbiota composition, the study hypothesizes that XN requires the microbiota to mediate its benefits.
Methods and Results
To test the hypothesis, the study feeds conventional and germ‐free male Swiss Webster mice either a low‐fat diet (LFD,...
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