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Le caspasi, una famiglia di proteasi della cisteina, sono i principali mediatori dell'apoptosi e dell'infiammazione. La caspasi-6 è classificata come effettore apoptotico e media il restringimento nucleare durante l'apoptosi, ma possiede meccanismi di attivazione e regolazione unici che differiscono da quelli di altre caspasi effettrici. Inoltre, crescenti prove hanno dimostrato che la caspasi-6 è...
Stroke is a disease caused by brain tissue damage because of blockage in the cerebrovascular system that disrupts body sensory and motoric systems Stroke disease is one of the highest death causes in the world. Data collection from Electronic Health Records (EHR) is increasing and has been included in the health service big data. It can be processed and analyzed using machine learning to determine...
Metabolomics has been increasingly applied in biomedical research and drug efficacy evaluation in the context of rapid advances in analytical instrumentation and bioinformatics. Metabolomics-based discovery will potentiate the drug development in many ways such as novel biomarkers discovery, precise clinical trial by stratifying patients, and evaluation of drug metabolism or toxicity. More translational...
The influence of temperature on cementitious composites is essential in infrastructures because of the potential hazards associated with fire. Fire response is dependent on the mechanical properties of cementitious composites or concretes. These properties vary significantly with temperature and also depend on heating rate and other environmental conditions. This paper discusses some important mechanical...
This study investigates the fundamental effects of electrical loads containing non-resistive components (e.g., rectifiers and capacitors) on piezoelectric energy harvesting performance. Theoretical, numerical and experimental studies have been carried out to investigate three types of electrical loads, namely (I) a rectifier followed by a resistor, (II) a rectifier followed by a regulating capacitor...
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