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Tah18–Dre2 is a recently identified yeast protein complex, which is highly conserved in human and has been implicated in the regulation of oxidative stress induced cell death and in cytosolic Fe‐S proteins synthesis. Tah18 is a diflavin oxido‐reductase with binding sites for flavin mononucleotide, flavin adenine dinucleotide and nicotinamide adenine dinucleotide phosphate, which is able to transfer...
Identification of unknown proteins subsequent to a mass spectrometry signal is still a serious obstacle in the discovery of relevant biomarkers of diagnostic interest.In this report the evaluation of a rational process under optimized conditions is described for three unknown proteins representing important targets in their field of investigation.The process, involving few dozens of chromatographic...
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