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In recent years, we demonstrated that prolonged (48-h) treatment of rats or mice with selective μ-opioid receptor (μOR) agonists induced a translocation of δ-opioid receptors (δORs) from intracellular compartments to neuronal plasma membranes in the dorsal horn of the spinal cord. It remained to be determined whether this phenomenon also occurred in the brain. To resolve this issue, we analyzed by...
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