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It has been demonstrated in vivo that lipid glycation products such as Amadori-glycated phosphatidylethanolamine (Amadori-PE) accumulate in the plasma of diabetic humans and animals, but how lipid glycation products are formed under hyperglycemic conditions are not clear. We sought to clarify the occurrence of lipid glycation and its relationships with lipid peroxidation and protein glycation during...
Human MRP14 (hMRP14) is a Ca 2+ -binding protein from the S100 family of proteins. This protein is co-expressed with human MRP8 (hMRP8), a homologue protein in myeloid cells, and plays an indispensable role in Ca 2+ -dependent functions during inflammation. This role includes the activation of Mac-1, the β 2 integrin which is involved in neutrophil adhesion to endothelial...
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