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α‐Synuclein (α‐Syn) is a presynaptic protein implicated in Parkinson's disease (PD). Mice overexpressing human wildtype (WT) α‐Syn under the Thy1 promoter show high levels of α‐Syn in cortical and subcortical regions, exhibit progressive sensorimotor anomalies, as well as non‐motor abnormalities and are considered models of pre‐manifest PD as there is little evidence of early loss of dopaminergic...
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