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Probabilistic atlases present prior knowledge about the spatial distribution of various structures or tissues in a population, used commonly in segmentation. We propose three methods for generating probabilistic atlases: 1) the atlases are constructed in a template space using dense non-rigid transformations and transformed to the space of unseen data, 2) as the method 1 but atlas selection is performed...
We present the first use of multi-region FDG-PET data for classification of subjects from the Alzheimer's Disease Neuroimaging Initiative. Image data were obtained from 69 healthy controls, 71 AD patients, and 147 patients with a baseline diagnosis of MCI. Anatomical segmentations were automatically generated in the native MRI-space of each subject, and the mean signal intensity per cubic millimetre...
An adaptive fuzzy c-means (AFCM) clustering based algorithm was developed and applied to the segmentation and classification of multi-color fluorescence in situ hybridization (M-FISH) images, which can be used to detect chromosomal abnormalities for cancer and genetic disease diagnosis. The algorithm improves the classical fuzzy c-means (FCM) clustering algorithm by introducing a gain field, which...
In this paper we propose a robust and fully automated lumbar herniation diagnosis system based on clinical MRI data which will not only aid a radiologist to make a decision with increased confidence, but will also reduce the time needed to analyze each case. Our method is based on three steps : 1) We automatically label the five lumbar intervertebral discs in a sagittal MRI slice using a probabilistic...
Boosting is a versatile machine learning technique that has numerous applications including but not limited to image processing, computer vision, data mining etc. It is based on the premise that the classification performance of a set of weak learners can be boosted by some weighted combination of them. There have been a number of boosting methods proposed in the literature, such as the AdaBoost,...
We propose an automatic color segmentation system that (1) incorporates domain knowledge to guide histological image segmentation and (2) normalizes images to reduce sensitivity to batch effects. Color segmentation is an important, yet difficult, component of image-based diagnostic systems. User-interactive guidance by domain experts-i.e., pathologists-often leads to the best color segmentation or...
Plaque composition analysis is a critical tool in identifying vulnerable atherosclerotic plaques. Intravascular ultrasound with spectral analysis of the backscattered radio frequency (RF) signals (IVUS-VH) is currently considered as the gold standard for the evaluation of coronary plaque composition, while CT coronary angiography (CTA) has been proposed as a potential non-invasive counterpart. In...
We propose a method for automatic emotion recognition as part of the FERA 2011 competition. The system extracts pyramid of histogram of gradients (PHOG) and local phase quantisation (LPQ) features for encoding the shape and appearance information. For selecting the key frames, K-means clustering is applied to the normalised shape vectors derived from constraint local model (CLM) based face tracking...
DEM availability and GIS-assisted processing of DEM have brought accelerated development of geomorphometry to a great extent. Based on analysis of the GTOPO30 DEM and its derivations (six terrain factors), relief form of China is classified. This method takes each terrain factor as a single-band image and combines the six single-band images into a multi-band image. Then object-oriented classification...
In multi-atlas based segmentation propagation, segmentations from multiple atlases are propagated to the target image and combined to produce the segmentation result. Local weighted voting (LWV) method is a classifier fusion method which combines the propagated atlases weighted by local image similarity. We demonstrate that the segmentation accuracy using LWV improves as the number of atlases increases...
In machine learning, non-linear dimensionality reduction (NLDR) is commonly used to embed high-dimensional data into a low-dimensional space while preserving local object adjacencies. However, the majority of NLDR methods define object adjacencies using distance metrics that do not account for the quality of the features in the high-dimensional space. In this paper we present Boosted Spectral Embedding...
We present a new semi-supervised algorithm for dimensionality reduction which exploits information of unlabeled data in order to improve the accuracy of image-based disease classification based on medical images. We perform dimensionality reduction by adopting the formalism of constrained matrix decomposition of to semi-supervised learning. In addition, we add a new regularization term to the objective...
Decoding perceptual or cognitive states based on brain activity measured using functional Magnetic Resonance Imaging (fMRI) can be achieved using machine learning algorithms to train classifiers of specific stimuli. However, the high dimensionality and intrinsically low Signal-to-Noise Ratio (SNR) of fMRI data poses great challenges to such techniques. The problem is aggravated in the case of multiple...
The objective of this research is to develop algorithm to recognize black germ wheat based on image processing. The sample used for this study involved wheat from major producing areas of China. Images of wheat were acquired with a color linear CCD machine vision system. Each image was pre-processed to correct color offset. Then double-threshold method was used to segment black germ from background...
Data reduction is an important step in knowledge discovery from data. The high dimensionality of databases can be reduced using suitable techniques, depending on the requirements of the data mining processes. In this work, Rough set theory (RST) has been used as such a tool with much success. RST enables the discovery of data dependencies and the reduction of the number of attributes contained in...
In this paper, Probabilistic Neural Network with image and data processing techniques was employed to implement an automated brain tumor classification. The conventional method for medical resonance brain images classification and tumors detection is by human inspection. Operator-assisted classification methods are impractical for large amounts of data and are also non-reproducible. Medical Resonance...
In this work, a combination of artificial neural network (ANN), Fourier descriptors (FD) and spatial domain analysis (SDA) has been proposed for the development of an automatic fruits identification and sorting system. Fruits images are captured using digital camera inclined at different angles to the horizontal. Segmentation is used for the classification of the preprocessed images into two non-overlapping...
A high rate of expression of Endothelin protein in the placental cell is very much regulated by inhalation of tobacco smoke and leads to placental abnormalities subjected to birth failure. Our application developed using Image Processing, Nearest Neighbor algorithm (NN) and Genetic Algorithms (GA), automates the study of these proteins to assist pathologists and lab technicians in achieving a more...
The combination of local features, complementary feature types, and relative position information has been successfully applied to many object-class recognition tasks. Stacking is a common classification approach that combines the results from multiple classifiers, having the added benefit of allowing each classifier to handle a different feature space. However, the standard stacking method by its...
As texture information among pixels can be effectively represented using Local binary patterns (LBPs), image descriptors built using LBPs or its variants have been frequently used for various image analysis applications, e.g. medical image and texture image classification and retrieval. However, neither LBP nor any of its existing variants can be used to build descriptors for classifying multimodal...
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