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Effective antibacterial coatings are in demand in medicine, especially for urological medical devices such as catheters and stents. We propose the production method of an antibacterial hydrogel coating on polydimethylsiloxane (PDMS, silicone), a popular surface for medical materials. The coating process consists of the following steps: PDMS surface activation (introduction of hydroxyl groups), silanisation...
The aim of this study was to evaluate the influence of the surface microstructure of chitosan films on the contact angle. Films without plasticising additives made of chitosan or regenerated chitosan were selected for the tests. A sessile drop method based on the European Pharmacopoeia was used to determine the contact angle. Due to the method of film production, the contact angle measurements were...
Chitosan are biopolymers that are actively used for the production of local haemostatic agents. The physicochemical characteristics that determine its biological properties include the molecular weight and the deacetylation degree. However, there is no linear relationship between these parameters and haemostatic activity. The most reliable method of confirming the effectiveness is still in vivo experiments...
Treatment of chitosan with ionising radiation is one of the methods by which it is modified for various applications. However, in the case of chitosan irradiated in the solid state, the radicals formed during irradiation can be stabilised in its crystalline phase and subsequently cause post-irradiation changes. It has been observed that further degradation of the polymer occurs during storage of the...
The aim of this research was to develop a bioadhesive film based on benzydamine hydrochloride incorporated into natural bioadhesive polymers with different quantities of chitosan and guar gum but utilising a plasticiser. The obtained gels were deaerated by sonification, formed and evaporated by hot air drying; then, the properties were evaluated. Guar gum had a great influence on mechanical properties...
The aim of this study was to develop a technical process and composition of mucoadhesive hydrogels containing benzocaine, based on different concentration ratios of the natural polymers chitosan and xanthan gum. For this purpose, lyophilisates of polymeric complexes with the quantitative ratios of 0.5:1, 1:1 and 1:0.5 chitosan to xanthan gum were prepared and subsequently used to prepare hydrogels...
The wetting properties of chitosan (Ch) and single 1,2-dipalmitoylsn-glycero-3-phosphocholine (DPPC), cholesterol (Chol) and binary DPPC-Chol layers deposited onto polyethylene terephthalate activated by low-temperature air plasma (PETair) were examined. PET is widely used in tissue engineering, but its low hydrophilicity limits its integration with the surrounding tissues. Ch is a biocompatible polysaccharide,...
Chitosan hydrolysate was obtained using nitric acid; the prevailing fraction had a molecular weight of 30 kDa and a deacetylation degree of 95%. The effect of chitosan hydrolysate when added to potato dextrose agar (PDA) in different concentrations (0.5, 1, 1.5, 2, 4, 6 and 8 mg/mL) was studied on the growth of the fungi Alternaria solani Sorauer, Fusarium solani (Mart.) Sacc. and Rhizoctonia solani...
Creating innovative methods of treatment and regeneration of damaged tissues or organs is a key challenge of the twenty-first century. The aim of this study was to determine the possibility of producing and characterising the properties of self-organising chitosan hydrogels prepared with the use of chitosan lactate/chloride and disodium hydrogen phosphate dodecahydrate as a cross-linking agent. The...
Food edible coatings are an important milestone in food production and one of the innovations in food packaging development. This article presents materials on the development of the formulation and technology for the manufacture of a novel composite coating based on sodium alginate, chitosan and protein hydrolysate obtained by the electrochemical method of double extraction from cod processing waste...
Nanocrystalline hydroxyapatite (n-HAp), which has low crystallinity, has attracted great attention due to its similarity to the inorganic part of human bone. Therefore, many studies have focused on creating new formulations combining n-HAp with some biopolymers, such as chitosan, in order to imitate biological bone tissue. The importance of chitosan and its derivatives in biomedical applications has...
Membranes were prepared using three chitosans with different molecular weights and degrees of deacetylation. The influence of chitosan features on membrane physicochemical properties, i.e. degree of swelling, contact angle and tensile strength, as well as membrane separation properties in ethanol dehydration by the vapour permeation process are discussed. The conducted experiments showed that an increase...
Plastic is undoubtedly the most convenient type of packaging, but at the same time it is not ecologically friendly. The widespread use of packaging materials all over the world makes us think more and more about the harm of plastic to the environment and humans. It does not decompose in natural conditions and accumulates in huge quantities, because it is mostly used as a single-use packaging. Therefore,...
This article presents data on the effect of processing avocado fruit on the dynamics of physiological and biochemical processes during low-temperature storage. The aim was to explore the effect of processing Fuerte avocado fruit with ‘Agrokhit’, ‘KHAN-8’ and ‘Extrasol-90’ preparations on the dynamics of physiological and biochemical processes during storage. The effectiveness of the preparations on...
Textile products enriched with natural substances, e.g. hyaluronic acid, plant hydrolates, collagen and chitosan, may find wide application in cosmetics because of increasing consumer interest in natural products. Furthermore, in view of global environmental pollution, products that are produced through biochemical changes as a result of composting are sought. This makes it possible to enter such...
Termites are insects that can damage buildings, paper and plants. Termites are controlled by using termiticides (chemicals). Besides polluting the environment, termiticides may have harmful effects to organisms, including humans, and destroy metal. The use of chemicals will be environmentally and economically profitless. A joint effort to utilize biodegradable material will help to reduce the negative...
The properties of one-component and mixed monolayers of phospholipid 1,2–dipalmitoyl–sn–glycero–3–phosphocholine (DPPC) and polypeptide cyclosporine A (CsA) on the chitosan subphase were studied. DPPC is the main component that builds biological membranes, and CsA is an immunosuppressive drug typically used in medicine to prevent transplant rejections. The stability and reversibility of compression...
In this work, we report a stepwise formation method of a chitosan/sodium alginate polyelectrolyte complex (CS/SA PEC) membrane. The proposed method aiming at the utilization of the ultrasonic treatment of chitosan and sodium alginate solution allowed us to obtain a highly homogeneous hybrid membrane for electrochemical usage. The CS/SA PEC membrane saturated in a 2 M Li2SO4 aqueous solution was used...
Hydrogel films composed of chitosan and agar or chitosan, agar and honey/bee pollen were prepared; they could be used as active wound dressings. During this study, various types of gel films were prepared using chitosan with different molecular weights and ratios of the two biopolymers. In addition, compositions with different amounts of honey or bee pollen were obtained. The selected samples were...
Damage to the nervous system, in particular spinal cord injuries, is a burden for the patient and is usually the cause of irreversible disability. The progress observed in the last decade in the fields of biology, biomaterial engineering and neurosurgery has created new treatment solutions while preventing further neurodegenerative processes. The most important research is focused on the implementation...
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