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Modern technology has taken great strides to restore motion to amputees with prostheses. A key limitation in many cases is lack of a reliable controlling interface to the prosthetic devices. To address this issue, our lab has developed the Regenerative Peripheral Nerve Interface (RPNI). RPNIs transduce signals between residual peripheral nerves, muscle grafts, and prosthetic devices. Prior to this...
The concept of digital microfluidic biochip is bound to revolutionize the speed, precision and reliability of clinical diagnosis, forensic investigations and drug testing mechanisms in medical science and pharmaceutical industries. This can usher in a new horizon in the health care scenario of human society. Structural testing of digital microfluidic biochips detects the defects in the cell based...
A digital micro fluidic biochip (DMFB) is an attractive platform for immunoassays, point-of-care clinical diagnostics, DNA sequencing, and other laboratory procedures in biochemistry. Effective testing methods are required to ensure robust DMFB operation and high confidence in the outcome of biochemical experiments. Prior work on DMFB testing does not address the problem of designing the test to minimize...
Pain is unpleasant sensory which is always a subjective measurement. Various studies try to find a solution to have life without pain. In critical situation, the treatment of burn patients need some criteria to understand a level of pain sensation. This study focuses on an acute thermal pain. The purpose of this study is to block the pain pathway using the transcutaneous electrical nerve stimulation...
Protection against electric shock requires grounding systems that must be designed primarily to keep touch voltage and step voltage below a safe value. The measurement of the ground resistance in a large grounding network requires to place current electrodes at adequate distances. In urban areas, buildings grow adjacent each other, and the choice of suitable locations for auxiliary electrodes becomes...
In this paper, a novel sEMG decoder was proposed for estimating the human intention. When the position of the electrode changes, most of the decoder cannot be used as it is and needs to be retrained with new data from changed electrode positions. In retraining, old training results are often discarded and a new decoder is trained with only the data gathered after the changes. Naturally the decoding...
A simple testing procedure has been developed in order to investigate and screen the current interruption capability of vacuum interrupter contact materials. A synthetic circuit delivering adjustable AC currents, followed by a pulsed of 21 kV peak for 2 seconds has been used. The electrical tests has been developed to reproduce the conditions close to a fault current rated at 12 kV; only the recovery...
An electrode created with maskless metallization of Cu tracks ablated with laser direct structuring on a liquid crystal polymer can never achieve a quality comparable to sputtered layers on silicon, but has the advantage of being molded into complex 3D structures. As these electrodes on molded interconnected devices can function as conductometric sensors capable of detecting ion changes in a liquid...
Microfluidic based biochips as a composite microsystem offers an alternative platform for conventional laboratory procedures. In recent years a new generation of such lab on chip devices namely Digital Microfluidic Biochip is emerged as a suitable application for concurrent and scalable integration of multiple bioassay protocols. Dependability and accuracy are major issues for safety critical applications...
Despite modern technological advances, the most widely available prostheses provide little functional recovery beyond basic grasping. Although sophisticated upper extremity prostheses are available, optimal prosthetic interfaces which give patients high-fidelity control of these artificial limbs are limited. We have developed a novel Regenerative Peripheral Nerve Interface (RPNI), which consists of...
Digital micro fluidics based biochips is expected to play an important role towards point-of-care diagnostics, drug discovery, prevention of bio-terrorism and other biochemical applications. Design and testing of biochips always remained a challenging area of research. Structural testing of these bio-MEMS is ensured by smooth movements of test droplets within the micro fluidic array. Partitioning...
In this paper we present a novel approach for biometric identification using electroencephalogram (EEG) signals based on features extracted with the Hilbert-Huang Transform (HHT). The instantaneous amplitude and the instantaneous frequency were computed after the HHT, and these were then used to generate the features for classification. The proposed system was evaluated using two publicly available...
Due to great use of touchscreens in mobile telephones and other electronic devices, there has been great evolution in this technology. Its wide applicability makes the touch sensor technology suitable for detection of specific components in urine, responsible for urinary tract infection (UTI). Integration of a touch sensor in a disposable probe tip to be used in UTI detection represents a powerful...
Myoelectric control can be used for a variety of applications including powered protheses and different human computer interface systems. The aim of this study is to investigate the formulation of myoelectric control as a multi-class distance-based classification of multidimensional sequences. More specifically, we investigate (1) estimation of multi-muscle activation sequences from multi-channel...
We describe for the first time the design, implementation, and testing of a telemetry controlled simultaneous stimulation and recording device (SRD) to deliver chronic intercortical microstimulation (ICMS) to physiologically identified sites in rat somatosensory cortex (SI) and test hypotheses that chronic ICMS strengthens interhemispheric pathways and leads to functional reorganization in the enhanced...
The mirror neuron system (MNS) in humans is thought to enable an individual's understanding of the meaning of actions performed by others and the potential imitation and learning of those actions. In humans, electroencephalographic (EEG) changes in sensorimotor a-band at central electrodes, which desynchronizes both during execution and observation of goal-directed actions (i.e., ц suppression), have...
The digital microfluidics technology has shown a great progress in the recent years. The testing of these types of biochips is crucial when used in widespread applications like clinical diagnostics, DNA sequencing, toxicity analysis etc. Thus these biochips must be tested adequately both offline after manufacturing and online during the biomedical assay. The MEDA based digital microfluidics offers...
The DC arc hazard is a great concern to industry. Quantitative arc-hazard assessments are performed on DC systems to determine a nearby worker's potential incident-energy exposure during an arcing event. Four viable DC assessment methods are reviewed in this paper. The most widely used model for predicting DC incident energy is based on Lee's theoretical arc model; the electrical arc power is determined...
According to the latest requirements of the advanced laser system, a 700 kA gas switch with graphite electrodes for pulsed power supply module has been developed. The paper describes the design, construction and testing of the high-current gas switch. Through the analysis of the electrodes erosion of different materials, high-density graphite is found to be suitable for electrodes of the gas switch...
The aim of the present paper is to investigate the appropriateness of a new testing way consisting in the use of one or more auxiliary electrodes at short distances. If correctly applied, the method gives always conservative results. In the measurement the leakage current distribution around the ground electrode introduces a systematic error that increase the gradients in the area influenced by the...
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