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Apart from the classic role of vitamin D, its hormonal active form, calcitriol is also characterized by pleiotropic effects on various organs and tissues. For the last several years, many researchers have shown an association between deficiency of vitamin D and the risk of type 2 diabetes mellitus (T2DM). Recent investigations suggested the need of vitamin D supplementation in T2DM prevention. It...
Medicinal plants play an important role for health care. Medicinal plants have ability to cure both infectious and non infectious diseases. According to an estimate about 25 % of medicines are derived from plants. The objective of the present study was to evaluate the antifungal activity of Feronia elephantum Correa by using Agar well diffusion assay. The fungal strains used in this research work...
A 59-year-old farmer was admitted to the Department of Trauma Surgery because of pain associated with the presence of a tumour on the side of the right thigh. The patient stated that his biggest problem was great difficulty in moving and handling agricultural machinery due to the aforementioned lesion. On physical examination, the patient presented with numerous cutaneous and subcutaneous neurofibromas,...
Paraneoplastic syndromes consist of disorders that accompany benign and malignant tumours, but are not directly related to mass effects or invasion by the primary tumour or its metastases. The pathophysiology of mostly paraneoplastic syndromes is not well known. The usual mechanism of their development is the aberrant production of substances (protein hormones, hormone precursors or hormone-like substances)...
Background. Proper vitamin D intake is important due to its pleiotropic effect. It seems that obese population is a groups at risk of the vitamin D deficiency. Objective. To assess the vitamin D status in 1-5-year-old children with simple obesity. Material and Methods. The study included 100 children: classified according to their body mass index (BMI) as obese – Group I (n=50) and non-obese – Group...
Ayurvedic medicines are considered to be the best systems of treatment in India and this system is spreading now globally. Natural products are also a part of our everyday life. Ethno veterinary medicine is developed by farmers in field and barns rather than and in scientific laboratories. It is less systematic, less formalized and usually transferred by word of mouth rather than writing. An ethnobotanical...
Garlic (Allium sativum L. fam. Alliaceae) is one of the most researched and best-selling herbal products on the market. For centuries it was used as a traditional remedy for most health-related disorders. Also, it is widely used as a food ingredient – spice and aphrodisiac. Garlic’s properties result from a combination of variety biologically active substances which all together are responsible for...
Flavonoids are a group of bioactive compounds that are extensively found in foodstuffs of plant origin. Their regular consumption is associated with reduced risk of a number of chronic diseases, including cancer, cardiovascular disease (CVD) and neurodegenerative disorders. Flavonoids are classified into subgroups based on their chemical structure: flavanones, flavones, flavonols, flavan-3-ols, anthocyanins...
The problem of significantly reduced drug use concerns particularly the infections caused by multi-resistant pathogens, especially Gram-negative bacteria. In this regard, interest is increasing in the known for nearly 50 years, but now frequently forgotten antibiotic – fosfomycin. Fosfomycin possesses high effectiveness for multidrug-resistant bacteria, comprising of extended-spectrum β-lactamases...
Head and neck cancers constitute the sixth most common malignant tumours worldwide, and are one of the majors problems of global public health. In the oral cavity there are several types of oral cancers, but around 90% are squamous cell carcinoma. Many different risk factors play a role in the etiology of head and neck cancer. The aim of this study is presentation from the aspect of molecular, viral...
HIV-1 or Human Immuno Deficiency Virus-1 is the main causative agent of Acquired Immuno Deficiency Syndrome (AIDS). Human host infected with HIV - 1 extensively harbours many viral variants but very little is known about the difference in pattern[17] of evolution of phylogenetic lineages of HIV-1 non recombinant, normal inter subtype recombinant and main two specific recombinant forms of HIV-1 i.e...
Background. Patients with obesity, including morbid obesity, commit numerous dietary mistakes. They prefer high-energy diets, but of poor nutritional value. Patients qualified for bariatric procedures show deficiencies in vitamins and minerals due to insufficient intake of vegetables, fruit and whole grain products. Objective. Analysis of dietary habits in morbidly obese patients prepared for bariatric...
The present study examines the research output and citation analysis in the field of Oncology, a branch of medical science which deals with the study and treatment of tumours, what we commonly know as cancer. Cancer as a disease is not confined to a particular region or a country, but is a global phenomenon and is still beyond the complete understanding and control of medicos. Research in the field...
Ionizing radiation may cause damage to living tissue by producing free radicals like reactive oxygen species (ROS). ROS can randomly react with lipids, proteins and nucleic acids of cell causing oxidative stress and damage in these macromolecules, leading to pathogenesis of chronic diseases and age related and also cancer. The first line of defense from the damaging effects of ROS is antioxidants,...
Background. According to the WHO data in January 2007, 14 million children were overweight in the countries of the European Union. The problem of childhood obesity should be considered as one of the biggest challenges facing twentyfirst century nutrition and pediatrics. Objective. The aim of this study was to show the correlation between energy, basic nutrients intake and BMI of school children aged...
A 25-year-old female patient with a history of oral contraceptive use was admitted to hospital because of exertional dyspnoea, palpitations, chest discomfort and weakness. Since the clinical presentation was suggestive of some heart disease the patient underwent echocardiography which revealed indirect signs of acute pulmonary embolism. The diagnosis was confirmed with multisliced computed tomography...
Histopathological research is very important in diagnosing human and animal diseases. Detection of histopathological changes during certain parasitic invasions is particularly important for differential diagnosis and often confirms the presence of parasitic diseases. Such studies allow also to conclude on the primary cause of the disease.
Human cystic echinococcosis (CE), caused by Echinococcus granulosus, is one of the most important and widespread parasitic zoonoses. As one of the problems that can be encountered after treating CE patients is the risk of postsurgical relapses or treatment failure, a long-term clinical and serological follow-up is required to evaluate the success and failure of therapy. Therefore, the aim of the present...
The work purpose: To develop, scientifically to prove and introduce medical-organizational model of protection of reproductive health of patients with inflammatory diseases of genitals. Materials and methods. The female population of fertile age with inflammatory diseases of the genitals, living in the Grodno area per 1954–2008 is studied. The system approach is used, following methods were applied:...
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