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Urinary bladder tumours account for approximately 1% of all tumours in dogs. The majority of them are epithelial in origin and malignant. Transitional cell carcinoma (TCC) is the most commonly diagnosed tumour of the urinary bladder. Malignant mesenchymal tumours in humans and animals are far less frequent than epithelial ones. Malignant mesenchymal urinary bladder tumours are represented by rabdomyosarcoma...
For many years research on tumour development focused exclusively on the functions of cancer cells. Less attention was paid to tumour-associated cells, which form the tumour microenvironment. Nowadays we know that inflammatory infiltration cells associated with tumour proliferation may have a pro-tumour or an anti-tumour effect. Current studies are focused on interaction (cross-talk) between cells...
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