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The prophylaxis of thromboembolic events represents a key point in the modern management of patients with non valvular atrial fibrillation (AF), both paroxysmal and persistent/permanent. Up to now, vitamin K antagonist (VKA) drugs are the first choice in thromboembolic prophylaxis. Their treatment limitations have lead to development and clinical experimental use of new molecules aimed to overcome...
Chronic conditions represent an urgent health-care challenge for three main reasons: 1) their frequency is increasing all over the world, mainly as a result of longer life expectancy; 2) they require complex, long-term response that goes beyond the acute-care hospital setting; and 3) they place a heavy burden on health-care systems.The authors conducted a critical review of the literature to obtain...
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