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Lithium ist die einzige Substanz, die in der aktuellen S3-Leitlinie zur Diagnostik und Therapie Bipolarer Störungen den höchsten Empfehlungsgrad zur Phasenprophylaxe bipolarer Störungen erhält und die in Studien ohne sog. „enriched design“ die Wirksamkeit zur Prävention sowohl manischer als auch depressiver Episoden zeigen konnte. Es ist daher begrüßenswert, dass in The Lancet nun mit einer systematischen...
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