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Objectives To study the range of urinary levels of 4,4′-methylenedianiline (MDA), a metabolite of methylenediphenyl diisocyanate (MDI), across factories in the polyurethane industries and to evaluate the validity of this biomarker to assess MDI occupational exposure. Methods Workers exposed to MDI, as well as non-occupationally exposed subjects, were studied and pre- and post-shift urine samples...
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